Enzymes (proteolytic enzymes) and its use in metablic therepay

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Pancreatic enzymes

Although many consider the diet to be the single most important approach to the treatment of any disease, pancreatic and/or proteolytic (protein digesting) enzymes are considered by many experts in alternative therapies to be the single most important adjunct of a natural, alternative, or complementary approach to cancer cure.

There are many physicians utilizing complimentary approaches to cancer therapy that do NOT use amygdalin b17 (Laetrile). The Naturopaths and other physicians that do not use amygdalin in their protocol, almost always rely on large doses of pancreatic or proteolytic enzymes. Even those physicians using amygdalin in their therapies recognize pancreatic and other proteolytic enzymes as an integral and absolutely essential part of laetrile therapy.

Although amygdalin may be employed in their prescribed therapies, many physicians using laetrile still use a large quantity of pancreatic and proteolytic enzymes. There are many reasons that pancreatic enzymes are so crucial in cancer therapy. First, malignant tumors wall themselves off with a negatively charged protein coating. Since your body’s killer cells are also negatively charged, the tumor is not recognized as a foreign entity. Instead, it is treated by the body’s immune system as normal tissue. Like facing the same poles of 2 magnets towards each other, the magnets repel each other. This is the picture of what occurs when killer cells approach what they recognize to be normal tissue. This is where proteolytic enzymes become ESSENTIAL.

Proteolytic simply means protein digesting. Although there are other very important functions of proteolytic enzymes, the primary function of enzymes with cancer patients is in the “deshielding” or digesting the protective coating of a tumor.  In order for the immune system to have a positive effect on malignancy, it must first be able to recognize a malignancy as a foreign invader. In order for other anti-tumor agents to have a measurable effect on a tumor, the protective coating must be digested.

Although enzymes are highly beneficial and downright crucial, this is not to insinuate that merely taking a lot of enzymes and doing nothing else is all that you need. The nutritional deficiency that permitted the condition to exist is still there. Although removing the protective protein coating on a tumor does not get rid of a tumor, it is an important step in helping your body recognize the condition. It is believed (with good reason) that proteolytic enzymes will also begin to digest the tumor itself if taken in sufficient quantities.

However it still does not correct the body’s poor functioning immune system, and just because enzymes may engage in tumor digestion does not mean that it is sufficient or a substitution for following sound nutritional practices and lifestyles. Therefore it is stressed once again that like laetrile, enzymes are part of a TOTAL nutritional approach and not a magic bullet approach to this deficiency condition.

One Answer to Cancer 

Dr. William Donald Kelley

In his book One Answer to Cancer {available from Cancer Control Society-Dr. William Donald Kelley, who treated his own very serious form of cancer over 30 years ago, proclaims the virtues of pancreatic and other proteolytic enzymes in combination with the standard nutritional approach using diet, lifestyle changes, and other supplements. However, Dr. Kelley who does not have anything bad to say about amygdalin, none the less, does not use it in his protocol. What he does use, are very large doses of pancreatic enzymes in combination with diet and lifestyle changes.

His theory, which mirrors that of many other experienced physicians in nutritional medicine, is that proteolytic enzymes not only breakdown and digest the protective protein coating of a tumor, but that they also directly engage in an attack on the tumor itself once the protein coating has been destroyed. Logically, this makes a lot of sense considering that malignant tumors contain very little and very weak enzyme inhibitors, unlike the normal cells that contain a large number of enzyme inhibitors. These inhibitors protect normal body proteins from being attacked and digested by enzymes that are ingested or produced by one’s own body.

This is one reason why digestive enzymes do not digest the portion of the small intestine known as the duodenum when the pancreas dumps enzymes into it during the second phase of digestion. Furthermore, enzymes are catalysts involved in a myriad of other bodily functions. It is virtually impossible to overdose on pancreatic enzymes because they are in and of themselves proteins. But they are proteins that digest and breakdown other proteins.

Types of proteolitic enzymes

There are a few varying opinions regarding which pancreatic enzymes are best. Dr. Kelley prefers a very large dose of a pancreatic enzyme called pancreatin.

Pancreatin is a crude substance produced and released by the pancreas that contains a plethora of individual pancreatic enzymes such as trypsin, chymotrypsin, lipase, amylase, etc.  Although all physicians experienced with enzymes agree that pancreatin is very important, most prefer to use a combination of more concentrated specific pancreatic enzymes along with pancreatin and potent vegetable based proteolytic enzymes such as bromelain and papain.

The reason that most physicians prefer more specific enzymes is because biochemistry and clinical studies have proven the potency and value of specific pancreatic enzymes such as trypsin and chymotrypsin. For example, trypsin is part of the makeup of pancreatin but produces a far superior capability of protein digestion than pancreatin by itself. And chymotrypsin (a-chymotrypsin) is far superior to trypsin in its protein digesting capability primarily because its structured in a manner that inhibits self-digestion. The value of chymotrypsin in cancer therapy was documented by researcher Dr. John Beard in the first quarter of the twentieth century. 

It has been shown that chymotrypsin is an extremely potent enzyme even in extremely low doses. Many therapeutic formulas containing chymotrypsin utilize less than 1/2 mg of chymotrypsin. You can find out more about research done by Dr. Beard by contacting the Cancer Control Society at the phone number previously mentioned.

There are also many physicians who insist on vegetable based enzymes only and have gotten success. Most of the time the enzyme bromelain and/or papain is used in high quantities to achieve this goal. However, most physicians realize that since your pancreas produces pancreatic enzymes, it is best to supplement with pancreatic enzymes because as previously mentioned, there are countless bodily functions influenced by enzymes.

About Wobenzym and Mucos


The best of both worlds is available and has been for some time. Two enzyme combinations produced in Germany by the Mucos Corporation in the 1960s called Wobenzym and Wobe-Mugos were the mainstay for physicians practicing alternative cancer therapies for decades.

These enzymes combined both pancreatic and vegetable- based enzymes. Some physicians used both of them, but eventually, most physicians began to only use the Wobenzym because it was the more potent of the two.

The Mucos corporation used a technology that was not being used by other enzyme manufacturers. When they put the enteric coating on their enzyme tablets, they used an alkaline (pH) sensitive coating, whereas others around the world were using a simple protein coating.

The alkaline (pH) sensitive coating virtually guaranteed that the enzyme tablet was delivered to the duodenum for maximum absorption. The protein coating was a little less reliable. First, the protein coating might be digested in the stomach, thereby subjecting some of or all of the enzymes in the tablet to destruction by stomach acid.

There was also the possibility that the protein coating may survive the duodenum that would cause the tablet to pass through the system completely undigested. Although the technology used by Mucos in the 1960s is now available to everyone, many still use a protein-based enteric coating on their enzymes if they use one at all! 

Since protecting a pancreatic enzyme from the ravages of stomach acid is crucial, one should never purchase a pancreatic enzyme tablet unless it declares that it is enteric-coated.

Nor should anyone ever purchase a pancreatic enzyme in a gelatin capsule.  With newer technology available to everyone in the industry, ideally, no one should purchase a pancreatic enzyme tablet unless it declares that the tablet is coated with an alkaline sensitive enteric coating or pH-sensitive enteric coating.

Forty years ago the Mucos corporation was the only one producing a quality enzyme tablet with an advanced protective enteric coating that contained both plant and pancreatic enzymes. At that time the Mucos produced enzymes were in nearly every complimentary physician’s protocol when dealing with situations that called for the use of proteolytic enzymes. However, much has changed in 40 years. 

No longer does the Mucos corporation have privileged knowledge in the manufacturing process of enzymes.  There are a number of physicians who continue using the Wobenzym and Wobe-Mugos enzymes produced by Mucos because of their long-standing and continued good reputation which still exists and is well deserved. However, more and more physicians are using enzymes that are produced in the United States using the same technologies with much greater potencies at lower prices.  They are less expensive because they are manufactured domestically, there are no international transportation costs or duties paid, and in the American tradition, they are being manufactured with the concept that they must be competitive in both price and quality. The Mucos Corporation maintains higher prices based on their history and good reputation, much like the pharmaceutical industry’s prices on name brand drugs versus a generic of equal quality. 

Michael Richardson

Michael Richardson

I am a nutritionist and healthcare practitioner with over 10 years of experience. I am a medical article writer, blog writer. My passion is to help people. My favorite quote is:  “Let food be thy medicine and medicine be thy food.” ― Hippocrates

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